Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
August 6, 2018
RegMed Investors’ (RMi) pre-open: why is the sector like a fishing hole?
August 6, 2018
RegMed Investors’ (RMi) pre-open: why is the sector like a fishing hole?
August 3, 2018
RegMed Investors’ (RMi) pre-open: a quiet day on the quarterly reporting front
August 2, 2018
RegMed Investors’ (RMi) closing bell; after a session of bouncing around, Q2 results recover share pricing losses
August 1, 2018
RegMed Investors’ (RMi) closing bell; what goes up precipitately, verves down as easy
August 1, 2018
RegMed Investors’ (RMi) pre-open: new month
July 31, 2018
RegMed Investors’ (RMi) closing bell; it was time for the sector to jump positive after 4 negative closes in 6 sessions
July 30, 2018
RegMed Investors’ (RMi) closing bell; is the sector suffering from investor impotence
July 27, 2018
RegMed Investors’ (RMi) closing bell; another crashing session
July 26, 2018
RegMed Investors’ (RMi) closing bell; a “craps” table sector with cold dice
35 companies, 1 interpreter!
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