Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
April 22, 2021
RegMed Investors’ (RMi) closing bell: a volatile market session with the cell and gene therapy sector maintaining altitude
April 21, 2021
RegMed Investors’ (RMi) closing bell: the come-backs, a far-cry from yesterday’s sector advance/decline (A/D) line
April 20, 2021
RegMed Investors’ (RMi) closing bell: another sell-off and downer for the sector
April 19, 2021
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector suffers from arrested development
April 15, 2021
RegMed Investors’ (RMi) closing bell: sector climbs again
April 14, 2021
RegMed Investors’ (RMi) closing bell: “the sure way of gambling is getting something for nothing” after a Tuesday bounce
April 13, 2021
RegMed Investors’ (RMi) closing bell: the gain and the pain with a spike, a flame -up and a shake-off after JNJ vaccine halted
April 12, 2021
RegMed Investors’ (RMi) closing bell: it was scary, staring at the cell and gene therapy sector abyss
April 9, 2021
RegMed Investors’ (RMi) closing bell: just another sector beat-down
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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