Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
June 25, 2020
RegMed Investors’ (RMi) closing bell: surge, purge and gorge
June 24, 2020
RegMed Investors’ (RMi) closing bell: infection growth spooks markets as I expected the downslide
June 23, 2020
RegMed Investors’ (RMi) closing bell: sell the green
June 22, 2020
RegMed Investors’ (RMi) closing bell: is the sector a proxy for getting back to some-sort of normal?
June 19, 2020
RegMed Investors’ (RMi) closing bell: coronavirus resurgences as early market gains were ruined
June 18, 2020
RegMed Investors’ (RMi) closing bell: volatility rages
June 17, 2020
RegMed Investors’ (RMi) closing bell: my post challenged optimism as to how long then the sector flip-flopped
June 16, 2020
RegMed Investors’ (RMi) closing bell: retail sales data offset rise in coronavirus infections
June 15, 2020
RegMed Investors’ (RMi) closing bell: an impressive comeback for the sector
June 13, 2020
RegMed Investors’ (RMi) closing bell: a surge with whiplash component
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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