Stemline Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing proprietary therapeutics that target cancer stem cells (CSCs) and tumor bulk. It develops StemScreen platform technology consisting of StemScreen-1 and StemScreen-2 for the identification of novel CSC-directed compounds. The company is developing SL-401, a biologic-drug conjugate, which has completed Phase I/II clinical trial for relapsed or refractory acute myeloid leukemia; and SL-701, a synthetic peptide vaccine that has completed two Phase I/II clinical trials for pediatric and adult high-grade gliomas. Its products under preclinical stage include SL-301, a small molecule gamma-secretase inhibitor that inhibits Notch, a pathway expressed by CSCs and tumor bulk of multiple cancer types; SL-101, a mAb-based compound that targets CD123; SL-201, a small molecule active against certain hematologic and solid tumor types; and SL-601, mAb-based compound that targets a cell surface marker on bladder CSCs. The company also in-licensed intellectual property directed to mAb-based therapeutics to validated oncology targets, including Glypican-3, Tie-1, CD133, Frizzled, Smoothened, and Patched. Stemline Therapeutics, Inc. was founded in 2003 and is based in New York, New York.
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RegMed Investors’ (RMi) pre-open indications, the Sirens are singing
June 5, 2017
RegMed Investors’ (RMi) closing bell, even ASCO can’t shake negative sentiment
June 2, 2017
RegMed Investors’ (RMi) pre-open indications, the sector is going where after a big reverse?
June 1, 2017
RegMed Investors’ (RMi) pre-open indications, the word the sector grapples with is trust
May 11, 2017
RegMed Investors’ (RMi) closing bell, breaking out is hard to do
May 10, 2017
RegMed Investors’ (RMi) pre-open indications, it’s time for a bounce
May 5, 2017
Regenerative Medicine Earnings Scorecard - Q1/2017 - to date
May 4, 2017
RegMed Investors’ (RMi) closing bell analysis, the sector stood up at the open and fell down at the close
35 companies, 1 interpreter!
Insight, foresight and recommendation
Stemline Therapeutics (STML) -- STML opened on 1/2/18 at $15.65 and closed on 3/31 at $15.85 and March at $16.75 with a high (3/6/18) at 17.20 ...
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