Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
December 29, 2017
RegMed Investors’ (RMi) closing bell; what’s pulling the sector along
December 28, 2017
RegMed Investors’ (RMi) closing bell; I couldn’t have said it better …
December 27, 2017
RegMed Investors’ (RMi) closing bell; the holiday hangover is abating
December 26, 2017
RegMed Investors’ (RMi) closing bell; the upside versus the downside
December 18, 2017
RegMed Investors’ (RMi) closing bell; opens up and stays positive yet, squeaky to close positive
December 15, 2017
RegMed Investors’ (RMi) closing bell; sector opened down, stayed depressed at the mid-day and closed neutral
December 12, 2017
RegMed Investors’ (RMi) closing bell; sentiment is more than a threat
December 12, 2017
RegMed Investors’ (RMi) pre-open indication: struggling for pricing position
December 11, 2017
RegMed Investors’ (RMi) closing bell; ASH giveth and taketh
December 8, 2017
RegMed Investors’ (RMi) closing bell; the newest version of an old normal
35 companies, 1 interpreter!
Insight, foresight and recommendation
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