Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
September 13, 2023
RegMed Investors (RMi) Closing Bell: cell and gene therapy sector runs out of gas
August 31, 2023
RegMed Investors (RMi) Closing Bell: the match was lit on August’s last trading session
August 30, 2023
RegMed Investors (RMi) Closing Bell: the myth and the reality of sector share pricing
August 25, 2023
RegMed Investors (RMi) Closing Bell: sector takes the line of least expectation as sector turns positive
August 23, 2023
RegMed Investors (RMi) Closing Bell: equites up, employees down
August 17, 2023
Reg Med Investors (RMi) Closing Bell: August deepens the cell and gene therapy share pricing abyss
August 16, 2023
Reg Med Investors (RMi) Closing Bell: sector equities sell-off again
August 15, 2023
Reg Med Investors (RMi) Closing Bell: contracting sentiment contributes to the brunt of sector selling
August 14, 2023
Reg Med Investors (RMi) Closing Bell: another week’s beginning of share pricing sector losers
August 11, 2023
Reg Med Investors (RMi) closing Bell: oscillating between gains and losses since the beginning of August
35 companies, 1 interpreter!
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