Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
August 9, 2023
RegMed Investors’ (RMi) pre-open: strolling down the lane of cratered earnings sessions
August 8, 2023
RegMed Investors’ (RMi) pre-open: earnings, earnings and more earnings
July 31, 2023
RegMed Investors’ (RMi) closing bell: July ends on high note while sector LPS (loss-per-share) earnings are about to start
July 25, 2023
RegMed Investors’ (RMi) closing bell: softening outlook
July 11, 2023
RegMed Investors’ (RMi) closing bell: caution seems to be the sector’s word for the session
June 29, 2023
RegMed Investors’ (RMi) closing bell: a stress test of cell and gene therapy sector defines its equities
June 27, 2023
RegMed Investors’ (RMi) closing bell: I told you yesterday, the cell and gene therapy sector would come back
June 15, 2023
RegMed Investors’ (RMi) closing bell: sector rises as jobless claims were flat
35 companies, 1 interpreter!
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