Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
March 17, 2023
RegMed Investors’ (RMi) closing bell: a second Black Swan event this week
March 16, 2023
RegMed Investors’ (RMi) closing bell: sector responds to being oversold reversing some declines
March 15, 2023
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector suffers from Autophobia
March 13, 2023
RegMed Investors’ (RMi) closing bell: sector equities turn up from being oversold clouded by SVB’s decline
March 10, 2023
RegMed Investors’ (RMi) closing bell: bad goes to worse and fear for cell and gene therapy sector cash positions
March 9, 2023
RegMed Investors’ (RMi) closing bell: the sector does the limbo dance and low it went?
March 8, 2023
RegMed Investors’ (RMi) closing bell: the cell/gene therapy sector opened down, climbed up and then fell back
March 7, 2023
RegMed Investors’ (RMi) closing bell: indexes sell-off after Jerome spoke
March 3, 2023
RegMed Investors’ (RMi) closing bell: sector gets a push pull
35 companies, 1 interpreter!
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