Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
February 27, 2023
RegMed Investors’ (RMi) closing bell: hunker down but, be aware of earnings backlash
February 22, 2023
RegMed Investors’ (RMi) closing bell: the sector’s continuous menace - sustainability
February 22, 2023
RegMed Investors’ (RMi) pre-open: pick-up a few of the oversold while we wait again for Jerome’s minutes
February 10, 2023
RegMed Investors’ (RMi) closing bell: sector shot down by inflationary “objects”
February 7, 2023
RegMed Investors’ (RMi) closing bell: the cell/gene therapy sector suffered tough love until late session to pop the A/D (advance/decline) Line positive
January 25, 2023
RegMed Investors’ (RMi) closing bell: sector finishes down yet, made strides late in session
January 6, 2023
RegMed Investors’ (RMi) closing bell: jobs economic data pushes market and cell/gene therapy sector uphill
January 3, 2023
RegMed Investors’ (RMi) closing bell: 2023 first session of pain as recessionary perceptions initiated sudden decline
December 19, 2022
RegMed Investors’ (RMi) closing bell: residual negativity haunts our universe of cell and gene therapy is severely damaged
December 16, 2022
RegMed Investors’ (RMi) closing bell: sector extends losses as selling pressure continues
35 companies, 1 interpreter!
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