Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
August 4, 2022
RegMed Investors’ (RMi) closing bell: gravity was not a downward force as anticipated
August 4, 2022
RegMed Investors’ (RMi) pre-open: post earnings, remember Isaac Newton’s apple, gravity caused a bonk on the head
August 3, 2022
RegMed Investors’ (RMi) closing bell: the sector parties to the upside, the question is what happens when the music ends
August 3, 2022
RegMed Investors’ (RMi) pre-open: earnings and more earnings with a few shots-in -the dark
August 2, 2022
RegMed Investors’ (RMi) closing bell: indexes are mixed as cell and therapy sector responds to being oversold with electronic trading
August 2, 2022
RegMed Investors’ (RMi) pre-open: earnings’ week expectation, can’t take them all to the bank
August 1, 2022
RegMed Investors’ (RMi) closing bell: an end of month tumble on Friday, a stumble on Monday, the first session of August
August 1, 2022
RegMed Investors’ (RMi) pre-open: will August be the month of my portfolio’s discontent?
July 29, 2022
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector tumbles
July 28, 2022
RegMed Investors’ (RMi) closing bell: a focus on long-term investments will ruin short and near-term portfolio performance
35 companies, 1 interpreter!
Insight, foresight and recommendation
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