Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
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February 6, 2024
RegMed Investors (RMi) Closing Bell: electronic trader were not conflicted, saw the decline, popped the cork to carbonate some fizz in the sector
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RegMed Investors’ (RMi) pre-open: sector’s investors are conflicted as share pricing declines contaminate potential buy attitude
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RegMed Investors (RMi) Closing Bell: cell and gene therapy sector passes more gas
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RegMed Investors (RMi) Closing Bell: What a tangled sector we invest, the cell and gene therapy universe
January 12, 2024
RegMed Investors (RMi) Closing Bell: a Friday’s opening jive followed by afternoon dive after 3-other weekly downfalls
January 5, 2024
RegMed Investors (RMi) Closing Bell: liquefying the sector from the pre-open thesis
January 4, 2024
RegMed Investors (RMi) Closing Bell: sector turnaround day as some value returns
December 28, 2023
RegMed Investors (RMi) Closing Bell: The volatility tug-of-war
December 8, 2023
RegMed Investors (RMi) Closing Bell: good, bad, conflicting news and a negative sector close
35 companies, 1 interpreter!
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Editor and Publisher ... Henry McCusker enters his tenth (10th) year at RegMed Investors