Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
November 10, 2021
RegMed Investors’ (RMi) closing bell: yet another pull-back that cut to the bone as the sector bleeds-out
November 10, 2021
RegMed Investors’ (RMi) pre-open: sector weakness should/could unfold some of the oversold
November 9, 2021
RegMed Investors’ (RMi) closing bell: sector takes yet another dive
November 9, 2021
RegMed Investors’ (RMi) pre-open: a sector retreat is not a defeat, it will just move directionally
November 8, 2021
RegMed Investors’ (RMi) closing bell: the sector faded even as small-cap stocks led on the upside and held near their highs
November 8, 2021
RegMed Investors’ (RMi) pre-open: "Skip to My (The) Lou" after a record close, a sector decline, more LPS (loss-per-share) earnings this week
November 6, 2021
RegMed Investors’ (RMi) closing bell: bag and tag ‘em, as LPS (loss-per-share) earnings define the week’s share pricing endings
November 5, 2021
RegMed Investors’ (RMi) pre-open: not so fast to the sector exit on Friday but, I'm still walking instead of running
November 4, 2021
RegMed Investors’ (RMi) closing bell: not quite wrong and almost totally correct
November 4, 2021
RegMed Investors’ (RMi) pre-open: there are sessions I am out-on-the-limb having brought a saw with me
35 companies, 1 interpreter!
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