Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
October 26, 2020
RegMed Investors’ (RMi) closing bell: markets decline as COVID-19 infections incline
October 20, 2020
RegMed Investors’ (RMi) closing bell: the hole in the sector just got deeper
October 19, 2020
RegMed Investors’ (RMi) pre-open: define strength and how long can it be sustainable
October 16, 2020
RegMed Investors’ (RMi) closing bell: a churning week – pockets of strength with a ending daily and solid sector showing
October 16, 2020
RegMed Investors’ (RMi) pre-open: buy the few bottoms and sell any highs
October 15, 2020
RegMed Investors’ (RMi) closing bell: what’s the next catalyst for the sector and markets
October 12, 2020
RegMed Investors’ (RMi) closing bell: speculation primes the market pump, dime it
October 9, 2020
RegMed Investors’ (RMi) closing bell: headed to the weekend with a smile from the market and a stuffed olive in the libation
October 8, 2020
RegMed Investors’ (RMi) closing bell: slipping and squeaking to a positive close
35 companies, 1 interpreter!
Insight, foresight and recommendation
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