Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
March 19, 2020
RegMed Investors’ (RMi) pre-open: bada bing bada boom and calling it as it should be the Wuhan virus from where it emanated
March 6, 2020
RegMed Investors’ (RMi): a big blip with a moderate comeback or a black swan
March 4, 2020
RegMed Investors’ (RMi): the trend is your friend until it isn’t as the market reprices the impact of the coronavirus
March 3, 2020
RegMed Investors’ (RMi) pre-open: uncertainty unsettles markets, I’ve been scratching the selling and profiteering itch
March 2, 2020
RegMed Investors’ (RMi) closing bell: markets are jumping and bringing the sector along for the ride
March 2, 2020
RegMed Investors’ (RMi) pre-open: another volatile start to the week
February 20, 2020
RegMed Investors’ (RMi) pre-open: underestimation of share pricing risk exposure
February 19, 2020
RegMed Investors’ (RMi) closing bell: are investors listening, earning’s season leaves whispers all through this and next month
35 companies, 1 interpreter!
Insight, foresight and recommendation
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