Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
December 13, 2022
RegMed Investors’ (RMi) closing bell: indexes slow and some sector gains evaporate post CPI release
December 9, 2022
RegMed Investors’ (RMi) closing bell: the bleed keeps spraying
November 29, 2022
RegMed Investors’ (RMi) closing bell: the pendulum swung
November 25, 2022
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector equities faltered Friday in a subdued trading session.
November 18, 2022
RegMed Investors’ (RMi) closing bell: this week the cell and gene therapy sector equities got “whacked’ on the knuckles, today it got a pat on the back!
November 3, 2022
RegMed Investors’ (RMi) closing bell: taking it in the shins as sector trips
November 3, 2022
RegMed Investors’ (RMi) pre-open: gains followed by pain; so, what’s on-tap - earnings
November 2, 2022
RegMed Investors’ (RMi) closing bell: We waited for Jerome and got the expected .75 basis point rate increase
November 2, 2022
RegMed Investors’ (RMi) pre-open: bracing for Fed’s policy decision
November 1, 2022
RegMed Investors’ (RMi) closing bell: markets dive as sector thrives, algorithms “rule’ in our favor
35 companies, 1 interpreter!
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