Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
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May 3, 2021
RegMed Investors’ (RMi) pre-open: a busy week for earnings
April 28, 2021
RegMed Investors’ (RMi) closing bell: I thought up-downs were an exercise
April 27, 2021
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector swings low again
April 23, 2021
RegMed Investors’ (RMi) closing bell: an answer to this a.m.’s question, “what will be sustainable”?
April 22, 2021
RegMed Investors’ (RMi) closing bell: a volatile market session with the cell and gene therapy sector maintaining altitude
April 20, 2021
RegMed Investors’ (RMi) closing bell: another sell-off and downer for the sector
April 12, 2021
RegMed Investors’ (RMi) closing bell: it was scary, staring at the cell and gene therapy sector abyss
April 9, 2021
RegMed Investors’ (RMi) closing bell: just another sector beat-down
35 companies, 1 interpreter!
Insight, foresight and recommendation
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