Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
August 12, 2021
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector flips positive at mid-day
August 12, 2021
RegMed Investors’ (RMi) pre-open: Low volume and declining breadth infects the cell and gene therapy sector
August 11, 2021
RegMed Investors’ (RMi) closing bell: volatility sucks pond water
August 10, 2021
RegMed Investors’ (RMi) closing bell: earnings’ season is not for the faint-of-heart sector investor
August 10, 2021
RegMed Investors’ (RMi) pre-open: says who and what, facts and supporting numbers need to validate opinion
August 9, 2021
RegMed Investors’ (RMi) closing bell: as good as gets in these markets as sentiment wains
August 9, 2021
RegMed Investors’ (RMi) pre-open: the earnings’ LPS (loss-per-share) keep coming
August 6, 2021
RegMed Investors’ (RMi) closing bell: Back from the morning’s brink, safety is managing risk
August 6, 2021
RegMed Investors’ (RMi) pre-open: safety is protecting from or not exposed to danger or risk
August 5, 2021
RegMed Investors’ (RMi) closing bell: cell and gene therapy sector’s hot with a low volume rally
35 companies, 1 interpreter!
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