Sangamo BioSciences, Inc., a clinical stage biopharmaceutical company, focuses on the research, development, and commercialization of engineered DNA-binding proteins as novel therapeutic products for unmet medical needs in the United States. Its zinc finger DNA-binding proteins (ZFPs) could be engineered to make ZFP nucleases (ZFNs) proteins, which could be used to modify DNA sequences in various ways for genome editing and gene regulation; and ZFP transcription factors (ZFP TFs) proteins could be used to turn genes on or off. The companys principal ZFP therapeutic is SB-728-T, a ZFN-modified autologous T-cell product, which is in Phase II and Phase I/II clinical trials for the treatment of human immunodeficiency virus and acquired immunodeficiency syndrome. It also develops CERE-110 that is in Phase II clinical trial for the treatment of Alzheimers disease. In addition, the company has ZFP therapeutic pre-clinical stage programs for hemophilia A and B, huntingtons disease, and hemoglobinopathies; and proprietary programs in the areas of lysosomal storage disorders. Further, it has ZFP therapeutic research stage programs in the areas of other monogenic diseases, including various immunodeficiencies, as well as central nervous system disorders and cancer immunotherapy. The company has collaboration and license agreements with Shire International GmbH and Biogen Idec Inc.; and strategic partnerships with Sigma-Aldrich Corporation, Dow AgroSciences, LLC, Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, and Hoffmann-La Roche Inc. Sangamo Biosciences, Inc. was founded in 1995 and is headquartered in Richmond, California.
October 12, 2021
RegMed Investors’ (RMi) closing bell: love the upside but, the highs won’t last as Q3 results are being prepared for disposition
October 1, 2021
RegMed Investors’ (RMi) closing bell: Back from the depths to close positive
September 30, 2021
RegMed Investors’ (RMi) closing bell: sector closes the month with a slip and fall
September 27, 2021
RegMed Investors’ (RMi) closing bell: risks are mounting as sentiment seems AWOL
September 23, 2021
Q2/21 Earnings - (LPS - loss-per-share) Results
September 9, 2021
RegMed Investors’ (RMi) closing bell: sentiment loads its soppiness
August 18, 2021
RegMed Investors’ (RMi) closing bell: another early rout but, with no comeback in the cell and gene therapy sector
August 18, 2021
RegMed Investors’ (RMi) pre-open: there are no easy targets as indications follow casino rules
August 13, 2021
RegMed Investors’ (RMi) closing bell: sector wavers with minimal percentage movement, low volume and lack of breath
35 companies, 1 interpreter!
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